| 000 | 05657nam a22006495i 4500 | ||
|---|---|---|---|
| 001 | 978-3-319-16104-4 | ||
| 003 | DE-He213 | ||
| 005 | 20201217111452.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 150429s2015 gw | s |||| 0|eng d | ||
| 020 |
_a9783319161044 _9978-3-319-16104-4 |
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| 024 | 7 |
_a10.1007/978-3-319-16104-4 _2doi |
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| 072 | 7 |
_aPSG _2bicssc |
|
| 072 | 7 |
_aTEC012010 _2bisacsh |
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| 072 | 7 |
_aPSG _2thema |
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| 082 | 0 | 4 |
_a664.001579 _223 |
| 245 | 1 | 4 |
_aThe Impact of Food Bioactives on Health _h[electronic resource] : _bin vitro and ex vivo models / _cedited by Kitty Verhoeckx, Paul Cotter, Iván López-Expósito, Charlotte Kleiveland, Tor Lea, Alan Mackie, Teresa Requena, Dominika Swiatecka, Harry Wichers. |
| 250 | _a1st ed. 2015. | ||
| 264 | 1 |
_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2015. |
|
| 300 |
_aXVII, 338 p. 57 illus., 35 illus. in color. _bonline resource. |
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| 336 | _btxt | ||
| 337 | _bc | ||
| 338 | _bcr | ||
| 347 |
_atext file _bPDF _2rda |
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| 500 | _aIT Carlow ebook | ||
| 505 | 0 | _aIntroduction -- Gastrointestinal digestion models, general introduction -- Static digestion models general introduction -- InfoGest consensus method -- Approaches to static digestion models -- Dynamic digestion models general introduction -- The TNO gastro-Intestinal Model (TIM) -- Dynamic Gastric Model (DGM) -- Human Gastric Simulator (Riddet model) -- The DIDGI® System -- General introduction to cells, cell lines and cell culture -- Epithelial cell models; General introduction -- Caco-2 cell line -- HT29 cell line -- The IPEC-J2 cell line -- Co-cultivation of Caco-2 and HT-29MT -- Innate and adaptive immune cells; General introduction -- THP-1 and U937 cells -- Peripheral blood mononuclear cells -- PBMC-derived T cells -- Dendritic Cells -- Co-culture Caco-2/ immune cells -- Enteroendocrine Cell Models: General introduction -- STC-1 cells -- NCI-H716 cells -- Murine GLUTag cells -- In vitro intestinal tissue models: General introduction -- Intestinal crypt organoids as experimental models -- Porcine ex vivo intestinal segment model -- Ussing chamber -- In vitro fermentation models: General Introduction -- One compartment fermentation model -- The TNO in vitro model of the colon - TIM-2 -- The Simulator of the Human Intestinal Microbial Ecosystem - SHIME® -- The computer-controlled multicompartmental dynamic model of the gastrointestinal system SIMGI. | |
| 506 | 0 | _aOpen Access | |
| 520 | _aThis book describes in vitro and ex vivo models that can be employed to investigate effects of digested food products on the GIT, or specific components thereof. Many such models exist and include, for example, those used to study digestion and fermentation in the small and large intestine, to investigate absorption (e.g. Ussing chamber, epithelial cell systems), and to research the immune and enteroendocrine responses (e.g. macrophages, dendritic cells, co-cultures). In each case, these respective assays and models are discussed, and tips and tricks concerning their proper use are given. The Impact of Food Bioactives on Health: In Vitro and Ex Vivo Models is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest. The book highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated, and highlights the strengths and weaknesses of the various assays. It is also an important resource for under-graduate students in the 'food and health' arena. | ||
| 650 | 0 |
_aMicrobiology. _9100690 |
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| 650 | 0 |
_aFood-Biotechnology. _997663 |
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| 650 | 0 |
_aHuman physiology. _94485 |
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| 650 | 1 | 4 |
_aFood Microbiology. _0https://scigraph.springernature.com/ontologies/product-market-codes/L23040 _956279 |
| 650 | 2 | 4 |
_aFood Science. _0https://scigraph.springernature.com/ontologies/product-market-codes/C15001 _997666 |
| 650 | 2 | 4 |
_aHuman Physiology. _0https://scigraph.springernature.com/ontologies/product-market-codes/B13004 _94485 |
| 700 | 1 |
_aVerhoeckx, Kitty. _9100691 |
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| 700 | 1 |
_aCotter, Paul. _9100692 |
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| 700 | 1 |
_aLópez-Expósito, Iván. _9100693 |
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| 700 | 1 |
_aKleiveland, Charlotte. _9100694 |
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| 700 | 1 |
_aLea, Tor. _9100695 |
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| 700 | 1 |
_aMackie, Alan. _9100696 |
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| 700 | 1 |
_aRequena, Teresa. _9100697 |
|
| 700 | 1 |
_aSwiatecka, Dominika. _9100698 |
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| 700 | 1 |
_aWichers, Harry. _9100699 |
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| 710 | 2 |
_aSpringerLink (Online service) _930940 |
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| 773 | 0 | _tSpringer Nature eBook | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319161037 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319157917 |
| 776 | 0 | 8 |
_iPrinted edition: _z9783319353661 |
| 856 | 0 |
_ySend a message to library staff if access to this online resource is unavailable _uhttps://tinyurl.com/y2hljxwd |
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| 856 | 4 | 0 |
_yLink to Springer open access ebook _uhttps://doi.org/10.1007/978-3-319-16104-4 |
| 912 | _aZDB-2-SBL | ||
| 912 | _aZDB-2-SXB | ||
| 912 | _aZDB-2-SOB | ||
| 999 |
_c49777 _d49777 |
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